Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope

A high-throughput screening protocol for evaluating chimeric, self-sufficient P450 biocatalysts and their mutants against a panel of substrates was developed, leading to the identification of a number of novel biooxidation activities.

Detalles Bibliográficos
Autores principales: Robin, Aélig, Köhler, Valentin, Jones, Alison, Ali, Afruja, Kelly, Paul P, O'Reilly, Elaine, Turner, Nicholas J, Flitsch, Sabine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252848/
https://www.ncbi.nlm.nih.gov/pubmed/22238522
http://dx.doi.org/10.3762/bjoc.7.173
Descripción
Sumario:A high-throughput screening protocol for evaluating chimeric, self-sufficient P450 biocatalysts and their mutants against a panel of substrates was developed, leading to the identification of a number of novel biooxidation activities.

Ejemplares similares