Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules

In this work we demonstrate chiral recognition of (+)- and (−)-ephedrine using a cyclodextrin-containing polymer. The supramolecular structures obtained by complexation of ephedrine and cyclodextrin were verified by 2-D ROESY NMR measurements. Dynamic light scattering showed clear differences in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gingter, Sabrina, Ritter, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252852/
https://www.ncbi.nlm.nih.gov/pubmed/22238526
http://dx.doi.org/10.3762/bjoc.7.177
_version_ 1782220682308878336
author Gingter, Sabrina
Ritter, Helmut
author_facet Gingter, Sabrina
Ritter, Helmut
author_sort Gingter, Sabrina
collection PubMed
description In this work we demonstrate chiral recognition of (+)- and (−)-ephedrine using a cyclodextrin-containing polymer. The supramolecular structures obtained by complexation of ephedrine and cyclodextrin were verified by 2-D ROESY NMR measurements. Dynamic light scattering showed clear differences in the mean coil size.
format Online
Article
Text
id pubmed-3252852
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-32528522012-01-11 Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules Gingter, Sabrina Ritter, Helmut Beilstein J Org Chem Letter In this work we demonstrate chiral recognition of (+)- and (−)-ephedrine using a cyclodextrin-containing polymer. The supramolecular structures obtained by complexation of ephedrine and cyclodextrin were verified by 2-D ROESY NMR measurements. Dynamic light scattering showed clear differences in the mean coil size. Beilstein-Institut 2011-11-10 /pmc/articles/PMC3252852/ /pubmed/22238526 http://dx.doi.org/10.3762/bjoc.7.177 Text en Copyright © 2011, Gingter and Ritter https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Gingter, Sabrina
Ritter, Helmut
Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title_full Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title_fullStr Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title_full_unstemmed Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title_short Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
title_sort chiral recognition of ephedrine: hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252852/
https://www.ncbi.nlm.nih.gov/pubmed/22238526
http://dx.doi.org/10.3762/bjoc.7.177
work_keys_str_mv AT gingtersabrina chiralrecognitionofephedrinehydrophilicpolymersbearingbcyclodextrinmoietiesaschiralsensitivehostmolecules
AT ritterhelmut chiralrecognitionofephedrinehydrophilicpolymersbearingbcyclodextrinmoietiesaschiralsensitivehostmolecules

Ejemplares similares