Cargando…

Continuous-flow hydration–condensation reaction: Synthesis of α,β-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst

A simple, practical and efficient continuous-flow hydration–condensation protocol was developed for the synthesis of α,β-unsaturated ketones starting from alkynes and aldehydes by employing a heterogeneous catalyst in a flow microwave. The procedure presents a straightforward and convenient access t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rueping, Magnus, Bootwicha, Teerawut, Baars, Hannah, Sugiono, Erli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2011
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252873/ https://www.ncbi.nlm.nih.gov/pubmed/22238547 http://dx.doi.org/10.3762/bjoc.7.198

Ejemplares similares

Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis
por: Rueping, Magnus, et al.
Publicado: (2012)

Synthesis of α,β-unsaturated ketones through nickel-catalysed aldehyde-free hydroacylation of alkynes
por: Rhlee, Joon Ho, et al.
Publicado: (2022)

A combined continuous microflow photochemistry and asymmetric organocatalysis approach for the enantioselective synthesis of tetrahydroquinolines
por: Sugiono, Erli, et al.
Publicado: (2013)

Two-Carbon Homologation of Aldehydes and Ketones to α,β-Unsaturated Aldehydes
por: Petroski, Richard J., et al.
Publicado: (2011)

Asymmetric bronsted acid catalysis
por: Rueping, Magnus, et al.
Publicado: (2016)

s-Block Metal Catalysts for the Hydroboration of Unsaturated Bonds
por: Magre, Marc, et al.
Publicado: (2022)

Ca(OH)(2)-Catalyzed Condensation of Aldehydes with Methyl ketones in Dilute Aqueous Ethanol: A Comprehensive Access to α,β-Unsaturated Ketones
por: Yu, Lei, et al.
Publicado: (2016)

Polyphenylene-Based Solid Acid as an Efficient Catalyst for Activation and Hydration of Alkynes
por: Liu, Yiyun, et al.
Publicado: (2020)

Alkynes as Synthetic Equivalents of Ketones and Aldehydes: A Hidden Entry into Carbonyl Chemistry
por: Alabugin, Igor V., et al.
Publicado: (2019)

Incorporating heterogeneous lacunary Keggin anions as efficient catalysts for solvent-free cyanosilylation of aldehydes and ketones
por: Malmir, Masoume, et al.
Publicado: (2022)

A Porous Polymer-Based Solid Acid Catalyst with Excellent Amphiphilicity: An Active and Environmentally Friendly Catalyst for the Hydration of Alkynes
por: Lei, Yizhu, et al.
Publicado: (2019)

Solvent-free cross aldol condensation of aldehydes and ketones over SrMo(1-x)Ni(x)O(3-δ) perovskite nanocrystals as heterogeneous catalysts
por: Kekana, Lebohang, et al.
Publicado: (2023)

Evidence for an enolate mechanism in the asymmetric Michael reaction of α,β-unsaturated aldehydes and ketones via a hybrid system of two secondary amine catalysts
por: Umekubo, Nariyoshi, et al.
Publicado: (2020)

Iodine/water-mediated deprotective oxidation of allylic ethers to access α,β-unsaturated ketones and aldehydes
por: Xue, Yuntian, et al.
Publicado: (2020)

Recent Advances in Copper-Based Solid Heterogeneous Catalysts for Azide–Alkyne Cycloaddition Reactions
por: Aflak, Noura, et al.
Publicado: (2022)

Copper-catalyzed cascade annulation of unsaturated α-bromocarbonyls with enynals: a facile access to ketones from aldehydes
por: Che, Chao, et al.
Publicado: (2016)

Efficient Copper-bisisoquinoline-based Catalysts for Selective Aerobic Oxidation of Alcohols to Aldehydes and Ketones
por: Shen, Hao-Yu, et al.
Publicado: (2007)

A Green Approach for Allylations of Aldehydes and Ketones: Combining Allylborate, Mechanochemistry and Lanthanide Catalyst
por: de Souza, Viviane P., et al.
Publicado: (2016)

Chemoselective Electrochemical Hydrogenation of Ketones and Aldehydes with a Well‐Defined Base‐Metal Catalyst
por: Fokin, Igor, et al.
Publicado: (2020)

Gold-catalyzed regioselective oxidation of propargylic carboxylates: a reliable access to α-carboxy-α,β-unsaturated ketones/aldehydes
por: Ji, Kegong, et al.
Publicado: (2013)

Transition Metal Catalyst‐Free, Base‐Promoted 1,2‐Additions of Polyfluorophenylboronates to Aldehydes and Ketones
por: Liu, Zhiqiang, et al.
Publicado: (2021)

Iodine-mediated hydration of alkynes on keto-functionalized scaffolds: mechanistic insight and the regiospecific hydration of internal alkynes
por: Lee, Zachary, et al.
Publicado: (2019)

Stable immobilization of aldehyde ketone reductase mutants containing nonstandard amino acids on an epoxy resin via strain-promoted alkyne–azide cycloaddition
por: Li, Huimin, et al.
Publicado: (2020)

Synthesis of biofuel precursors from benzaldehyde and cyclopentanone via aldehyde–ketone condensation in a deep eutectic solvent system
por: Cao, Yunqi, et al.
Publicado: (2023)

Tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP): Efficient Catalysts for the Cyanosilylation and Cyanocarbonation of Aldehydes and Ketones
por: Matsukawa, Satoru, et al.
Publicado: (2009)

Highly selective and robust single-atom catalyst Ru(1)/NC for reductive amination of aldehydes/ketones
por: Qi, Haifeng, et al.
Publicado: (2021)

Thionation of Some α,β-Unsaturated Steroidal Ketones
por: Krstić, Natalija M., et al.
Publicado: (2010)

Enantioselective conjugate hydrosilylation of α,β-unsaturated ketones
por: Yang, Huan, et al.
Publicado: (2019)

Silyl Anion Initiated Hydroboration of Aldehydes and Ketones
por: Stanford, Martin W., et al.
Publicado: (2020)

Regioselective Hydroalkylation and Arylalkylation of Alkynes by Photoredox/Nickel Dual Catalysis: Application and Mechanism
por: Yue, Huifeng, et al.
Publicado: (2020)

Pathological Role of Unsaturated Aldehyde Acrolein in Diabetic Retinopathy
por: Murata, Miyuki, et al.
Publicado: (2020)

Preparation of α-Perfluoroalkyl Ketones from α,β-Unsaturated Ketones via Formal Hydroperfluoroalkylation
por: Jana, Kalipada, et al.
Publicado: (2021)

Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
por: Yu, Chuan-Ji, et al.
Publicado: (2009)

Highly regioselective synthesis of lactams via cascade reaction of α,β-unsaturated ketones, ketoamides, and DBU as a catalyst
por: Qin, Xin, et al.
Publicado: (2023)

Recyclable Catalysts for Alkyne Functionalization
por: Trigoura, Leslie, et al.
Publicado: (2021)

Activity and stability studies of H-transfer reduction reactions of aldehydes and ketones over aluminium isopropoxide heterogenised catalysts
por: Muhammad, Atika, et al.
Publicado: (2022)

Li vs Na: Divergent Reaction Patterns between Organolithium and Organosodium Complexes and Ligand-Catalyzed Ketone/Aldehyde Methylenation
por: Davison, Nathan, et al.
Publicado: (2023)

Efficient synthesis of β’-amino-α,β-unsaturated ketones
por: Abrunhosa-Thomas, Isabelle, et al.
Publicado: (2013)

Oxaphospholes and Bisphospholes from Phosphinophosphonates and α,β-Unsaturated Ketones
por: Arkhypchuk, Anna I, et al.
Publicado: (2013)

STIMULATION OF TARSAL RECEPTORS OF THE BLOWFLY BY ALIPHATIC ALDEHYDES AND KETONES
por: Chadwick, L. E., et al.
Publicado: (1949)

Cannot write session to /tmp/vufind_sessions/sess_8c9msvkphqgs5cetulnrb8ucd8