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The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina

The mouse retina is vascularized after birth when angiogenic blood vessels grow and sprout along a pre-formed latticework of astrocytes. How astrocyte-derived cues control patterns of blood vessel growth and sprouting, however, remains enigmatic. Here, we have used molecular genetic strategies in mi...

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Detalles Bibliográficos
Autores principales: Hirota, Shinya, Liu, Qian, Lee, Hye Shin, Hossain, Mohammad G., Lacy-Hulbert, Adam, McCarty, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253036/
https://www.ncbi.nlm.nih.gov/pubmed/22069187
http://dx.doi.org/10.1242/dev.069153