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Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation
BACKGROUND: Obesity is characterized by inflammation, caused by increase in proinflammatory cytokines, a key factor for the development of insulin resistance. SR141716A, a cannabinoid receptor 1 (CB1) antagonist, shows significant improvement in clinical status of obese/diabetic patients. Therefore,...
Autores principales: | Murumalla, Ravi, Bencharif, Karima, Gence, Lydie, Bhattacharya, Amritendu, Tallet, Frank, Gonthier, Marie-Paule, Petrosino, Stefania, di Marzo, Vincenzo, Cesari, Maya, Hoareau, Laurence, Roche, Régis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253048/ https://www.ncbi.nlm.nih.gov/pubmed/22087859 http://dx.doi.org/10.1186/1476-9255-8-33 |
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