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Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat

BACKGROUND: Central sensitization requires the activation of various intracellular signalling pathways within spinal dorsal horn neurons, leading to a lowering of activation threshold and enhanced responsiveness of these cells. Such plasticity contributes to the manifestation of chronic pain states...

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Detalles Bibliográficos
Autores principales:	Marchand, Fabien, D'Mello, Richard, Yip, Ping K, Calvo, Margarita, Muller, Emilie, Pezet, Sophie, Dickenson, Anthony H, McMahon, Stephen B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253059/ https://www.ncbi.nlm.nih.gov/pubmed/22054645 http://dx.doi.org/10.1186/1744-8069-7-86

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