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Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation

BACKGROUND: Pancreas cancer is one of most aggressive human cancers with the survival rate for patients with metastatic pancreas cancer at 5-6 months. The poor survival demonstrates a clear need for better target identification, drug development and new therapeutic strategies. Recent discoveries hav...

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Detalles Bibliográficos
Autores principales:	Vo, Kevin, Amarasinghe, Barushi, Washington, Kay, Gonzalez, Adriana, Berlin, Jordan, Dang, Thao P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253061/ https://www.ncbi.nlm.nih.gov/pubmed/22074495 http://dx.doi.org/10.1186/1476-4598-10-138

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