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Metabolic Regulation of Invadopodia and Invasion by Acetyl-CoA Carboxylase 1 and De novo Lipogenesis

Invadopodia are membrane protrusions that facilitate matrix degradation and cellular invasion. Although lipids have been implicated in several aspects of invadopodia formation, the contributions of de novo fatty acid synthesis and lipogenesis have not been defined. Inhibition of acetyl-CoA carboxyla...

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Detalles Bibliográficos
Autores principales:	Scott, Kristen E. N., Wheeler, Frances B., Davis, Amanda L., Thomas, Michael J., Ntambi, James M., Seals, Darren F., Kridel, Steven J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253107/ https://www.ncbi.nlm.nih.gov/pubmed/22238651 http://dx.doi.org/10.1371/journal.pone.0029761

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