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A Note on False Positives and Power in G × E Modelling of Twin Data
The variance components models for gene–environment interaction proposed by Purcell in 2002 are widely used. In both the bivariate and the univariate parameterization of these models, the variance decomposition of trait T is a function of moderator M. We show that if M and T are correlated, and mode...
Autores principales: | van der Sluis, Sophie, Posthuma, Danielle, Dolan, Conor V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253285/ https://www.ncbi.nlm.nih.gov/pubmed/21748401 http://dx.doi.org/10.1007/s10519-011-9480-3 |
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