Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas

A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MR...

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Detalles Bibliográficos
Autores principales: Onur, Mehmet Ruhi, Yalnız, Mehmet, Poyraz, Ahmet Kursad, Özercan, Ibrahim Hanifi, Ozkan, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253409/
https://www.ncbi.nlm.nih.gov/pubmed/22247642
http://dx.doi.org/10.3348/kjr.2012.13.1.94
Descripción
Sumario:A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.

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