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Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas
A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MR...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Radiology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253409/ https://www.ncbi.nlm.nih.gov/pubmed/22247642 http://dx.doi.org/10.3348/kjr.2012.13.1.94 |
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author | Onur, Mehmet Ruhi Yalnız, Mehmet Poyraz, Ahmet Kursad Özercan, Ibrahim Hanifi Ozkan, Yusuf |
author_facet | Onur, Mehmet Ruhi Yalnız, Mehmet Poyraz, Ahmet Kursad Özercan, Ibrahim Hanifi Ozkan, Yusuf |
author_sort | Onur, Mehmet Ruhi |
collection | PubMed |
description | A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis. |
format | Online Article Text |
id | pubmed-3253409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Society of Radiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-32534092012-01-13 Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas Onur, Mehmet Ruhi Yalnız, Mehmet Poyraz, Ahmet Kursad Özercan, Ibrahim Hanifi Ozkan, Yusuf Korean J Radiol Case Report A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis. The Korean Society of Radiology 2012 2011-12-23 /pmc/articles/PMC3253409/ /pubmed/22247642 http://dx.doi.org/10.3348/kjr.2012.13.1.94 Text en Copyright © 2012 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Onur, Mehmet Ruhi Yalnız, Mehmet Poyraz, Ahmet Kursad Özercan, Ibrahim Hanifi Ozkan, Yusuf Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title | Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title_full | Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title_fullStr | Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title_full_unstemmed | Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title_short | Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas |
title_sort | pancreatic islet cell amyloidosis manifesting as a large pancreas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253409/ https://www.ncbi.nlm.nih.gov/pubmed/22247642 http://dx.doi.org/10.3348/kjr.2012.13.1.94 |
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