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Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities
New drugs are urgently needed for the treatment of tropical and subtropical parasitic diseases, such as African sleeping sickness, Chagas' disease, leishmaniasis and malaria. Enzymes in polyamine biosynthesis and thiol metabolism, as well as polyamine transporters, are potential drug targets wi...
Autores principales: | Birkholtz, Lyn-Marie, Williams, Marni, Niemand, Jandeli, Louw, Abraham I., Persson, Lo, Heby, Olle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253432/ https://www.ncbi.nlm.nih.gov/pubmed/21834794 http://dx.doi.org/10.1042/BJ20110362 |
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