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Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin

Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU...

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Autores principales: Cruz, Milagros, Fernández-Alonso, Ana M., Rodríguez, Isabel, Garrigosa, Loreto, Caño, Africa, Carretero, Pilar, Vizcaíno, Amelia, Gonzalez-Ramirez, Amanda Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253471/
https://www.ncbi.nlm.nih.gov/pubmed/22242023
http://dx.doi.org/10.1155/2011/548327
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author Cruz, Milagros
Fernández-Alonso, Ana M.
Rodríguez, Isabel
Garrigosa, Loreto
Caño, Africa
Carretero, Pilar
Vizcaíno, Amelia
Gonzalez-Ramirez, Amanda Rocío
author_facet Cruz, Milagros
Fernández-Alonso, Ana M.
Rodríguez, Isabel
Garrigosa, Loreto
Caño, Africa
Carretero, Pilar
Vizcaíno, Amelia
Gonzalez-Ramirez, Amanda Rocío
author_sort Cruz, Milagros
collection PubMed
description Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events.
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spelling pubmed-32534712012-01-12 Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin Cruz, Milagros Fernández-Alonso, Ana M. Rodríguez, Isabel Garrigosa, Loreto Caño, Africa Carretero, Pilar Vizcaíno, Amelia Gonzalez-Ramirez, Amanda Rocío Obstet Gynecol Int Clinical Study Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events. Hindawi Publishing Corporation 2011 2011-12-26 /pmc/articles/PMC3253471/ /pubmed/22242023 http://dx.doi.org/10.1155/2011/548327 Text en Copyright © 2011 Milagros Cruz et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Cruz, Milagros
Fernández-Alonso, Ana M.
Rodríguez, Isabel
Garrigosa, Loreto
Caño, Africa
Carretero, Pilar
Vizcaíno, Amelia
Gonzalez-Ramirez, Amanda Rocío
Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_full Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_fullStr Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_full_unstemmed Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_short Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_sort postcesarean thromboprophylaxis with two different regimens of bemiparin
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253471/
https://www.ncbi.nlm.nih.gov/pubmed/22242023
http://dx.doi.org/10.1155/2011/548327
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