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Decrease in the production of beta-amyloid by berberine inhibition of the expression of beta-secretase in HEK293 cells
BACKGROUND: Berberine (BER), the major alkaloidal component of Rhizoma coptidis, has multiple pharmacological effects including inhibition of acetylcholinesterase, reduction of cholesterol and glucose levels, anti-inflammatory, neuroprotective and neurotrophic effects. It has also been demonstrated...
Autores principales: | Zhu, Feiqi, Wu, Fujun, Ma, Ying, Liu, Guangjian, Li, Zhong, Sun, Yong'an, Pei, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253691/ https://www.ncbi.nlm.nih.gov/pubmed/22152059 http://dx.doi.org/10.1186/1471-2202-12-125 |
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