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Tissue Engineering of the Penis
Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue av...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/ https://www.ncbi.nlm.nih.gov/pubmed/22235188 http://dx.doi.org/10.1100/2011/323989 |
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author | Patel, Manish N. Atala, Anthony |
author_facet | Patel, Manish N. Atala, Anthony |
author_sort | Patel, Manish N. |
collection | PubMed |
description | Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability. |
format | Online Article Text |
id | pubmed-3253692 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | TheScientificWorldJOURNAL |
record_format | MEDLINE/PubMed |
spelling | pubmed-32536922012-01-10 Tissue Engineering of the Penis Patel, Manish N. Atala, Anthony ScientificWorldJournal Review Article Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability. TheScientificWorldJOURNAL 2011-12-29 /pmc/articles/PMC3253692/ /pubmed/22235188 http://dx.doi.org/10.1100/2011/323989 Text en Copyright © 2011 M. N. Patel and A. Atala. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Patel, Manish N. Atala, Anthony Tissue Engineering of the Penis |
title | Tissue Engineering of the Penis |
title_full | Tissue Engineering of the Penis |
title_fullStr | Tissue Engineering of the Penis |
title_full_unstemmed | Tissue Engineering of the Penis |
title_short | Tissue Engineering of the Penis |
title_sort | tissue engineering of the penis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/ https://www.ncbi.nlm.nih.gov/pubmed/22235188 http://dx.doi.org/10.1100/2011/323989 |
work_keys_str_mv | AT patelmanishn tissueengineeringofthepenis AT atalaanthony tissueengineeringofthepenis |