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Tissue Engineering of the Penis

Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue av...

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Detalles Bibliográficos
Autores principales: Patel, Manish N., Atala, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/
https://www.ncbi.nlm.nih.gov/pubmed/22235188
http://dx.doi.org/10.1100/2011/323989
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author Patel, Manish N.
Atala, Anthony
author_facet Patel, Manish N.
Atala, Anthony
author_sort Patel, Manish N.
collection PubMed
description Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability.
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spelling pubmed-32536922012-01-10 Tissue Engineering of the Penis Patel, Manish N. Atala, Anthony ScientificWorldJournal Review Article Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability. TheScientificWorldJOURNAL 2011-12-29 /pmc/articles/PMC3253692/ /pubmed/22235188 http://dx.doi.org/10.1100/2011/323989 Text en Copyright © 2011 M. N. Patel and A. Atala. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Patel, Manish N.
Atala, Anthony
Tissue Engineering of the Penis
title Tissue Engineering of the Penis
title_full Tissue Engineering of the Penis
title_fullStr Tissue Engineering of the Penis
title_full_unstemmed Tissue Engineering of the Penis
title_short Tissue Engineering of the Penis
title_sort tissue engineering of the penis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253692/
https://www.ncbi.nlm.nih.gov/pubmed/22235188
http://dx.doi.org/10.1100/2011/323989
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