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Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: co...

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Detalles Bibliográficos
Autores principales: Sáinz, Neira, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Ramírez, Beatriz, Lancha, Andoni, Burgos-Ramos, Emma, Gómez-Ambrosi, Javier, Frühbeck, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253781/
https://www.ncbi.nlm.nih.gov/pubmed/22253718
http://dx.doi.org/10.1371/journal.pone.0029389