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Stable Extracellular RNA Fragments of Mycobacterium tuberculosis Induce Early Apoptosis in Human Monocytes via a Caspase-8 Dependent Mechanism

The molecular basis of pathogen-induced host cell apoptosis is well characterized for a number of microorganisms. Mycobacterium tuberculosis is known to induce apoptosis and it was shown that live but not heat killed M. tuberculosis stimulates this biological pathway in monocytes. The dependence of...

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Detalles Bibliográficos
Autores principales:	Obregón-Henao, Andrés, Duque-Correa, María A., Rojas, Mauricio, García, Luis F., Brennan, Patrick J., Ortiz, Blanca L., Belisle, John T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253812/ https://www.ncbi.nlm.nih.gov/pubmed/22253841 http://dx.doi.org/10.1371/journal.pone.0029970

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