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Primitive Neuroectodermal Tumor of the Liver: A Case Report

Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admit...

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Autores principales: Cambruzzi, Eduardo, Guerra, Enilde Eloena, Hilgert, Hamilton Cardoso, Schmitz, Herbert Jorge, Silva, Vinícius Lopes, Milani, Daniel Marini, Cruz, Ricardo Pedrini, Pruinelli, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254232/
https://www.ncbi.nlm.nih.gov/pubmed/22242031
http://dx.doi.org/10.1155/2011/748194
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author Cambruzzi, Eduardo
Guerra, Enilde Eloena
Hilgert, Hamilton Cardoso
Schmitz, Herbert Jorge
Silva, Vinícius Lopes
Milani, Daniel Marini
Cruz, Ricardo Pedrini
Pruinelli, Raul
author_facet Cambruzzi, Eduardo
Guerra, Enilde Eloena
Hilgert, Hamilton Cardoso
Schmitz, Herbert Jorge
Silva, Vinícius Lopes
Milani, Daniel Marini
Cruz, Ricardo Pedrini
Pruinelli, Raul
author_sort Cambruzzi, Eduardo
collection PubMed
description Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients.
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spelling pubmed-32542322012-01-12 Primitive Neuroectodermal Tumor of the Liver: A Case Report Cambruzzi, Eduardo Guerra, Enilde Eloena Hilgert, Hamilton Cardoso Schmitz, Herbert Jorge Silva, Vinícius Lopes Milani, Daniel Marini Cruz, Ricardo Pedrini Pruinelli, Raul Case Rep Med Case Report Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients. Hindawi Publishing Corporation 2011 2011-12-27 /pmc/articles/PMC3254232/ /pubmed/22242031 http://dx.doi.org/10.1155/2011/748194 Text en Copyright © 2011 Eduardo Cambruzzi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cambruzzi, Eduardo
Guerra, Enilde Eloena
Hilgert, Hamilton Cardoso
Schmitz, Herbert Jorge
Silva, Vinícius Lopes
Milani, Daniel Marini
Cruz, Ricardo Pedrini
Pruinelli, Raul
Primitive Neuroectodermal Tumor of the Liver: A Case Report
title Primitive Neuroectodermal Tumor of the Liver: A Case Report
title_full Primitive Neuroectodermal Tumor of the Liver: A Case Report
title_fullStr Primitive Neuroectodermal Tumor of the Liver: A Case Report
title_full_unstemmed Primitive Neuroectodermal Tumor of the Liver: A Case Report
title_short Primitive Neuroectodermal Tumor of the Liver: A Case Report
title_sort primitive neuroectodermal tumor of the liver: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254232/
https://www.ncbi.nlm.nih.gov/pubmed/22242031
http://dx.doi.org/10.1155/2011/748194
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