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Primitive Neuroectodermal Tumor of the Liver: A Case Report
Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254232/ https://www.ncbi.nlm.nih.gov/pubmed/22242031 http://dx.doi.org/10.1155/2011/748194 |
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author | Cambruzzi, Eduardo Guerra, Enilde Eloena Hilgert, Hamilton Cardoso Schmitz, Herbert Jorge Silva, Vinícius Lopes Milani, Daniel Marini Cruz, Ricardo Pedrini Pruinelli, Raul |
author_facet | Cambruzzi, Eduardo Guerra, Enilde Eloena Hilgert, Hamilton Cardoso Schmitz, Herbert Jorge Silva, Vinícius Lopes Milani, Daniel Marini Cruz, Ricardo Pedrini Pruinelli, Raul |
author_sort | Cambruzzi, Eduardo |
collection | PubMed |
description | Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients. |
format | Online Article Text |
id | pubmed-3254232 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32542322012-01-12 Primitive Neuroectodermal Tumor of the Liver: A Case Report Cambruzzi, Eduardo Guerra, Enilde Eloena Hilgert, Hamilton Cardoso Schmitz, Herbert Jorge Silva, Vinícius Lopes Milani, Daniel Marini Cruz, Ricardo Pedrini Pruinelli, Raul Case Rep Med Case Report Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its largest dimension. On the histopathology, a tumor composed of small round blue cells with little cytoplasm and round nuclei was identified. The lesion revealed positive immunoexpression for vimentin and CD99 and negative immunostaining for desmin, CD45, cytokeratin, and neuroblastoma protein, suggesting, then, the diagnosis of PNET. Although it is an unusual tumor, it should be considered in the differential diagnosis of liver masses, especially in young patients. Hindawi Publishing Corporation 2011 2011-12-27 /pmc/articles/PMC3254232/ /pubmed/22242031 http://dx.doi.org/10.1155/2011/748194 Text en Copyright © 2011 Eduardo Cambruzzi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cambruzzi, Eduardo Guerra, Enilde Eloena Hilgert, Hamilton Cardoso Schmitz, Herbert Jorge Silva, Vinícius Lopes Milani, Daniel Marini Cruz, Ricardo Pedrini Pruinelli, Raul Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title_full | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title_fullStr | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title_full_unstemmed | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title_short | Primitive Neuroectodermal Tumor of the Liver: A Case Report |
title_sort | primitive neuroectodermal tumor of the liver: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254232/ https://www.ncbi.nlm.nih.gov/pubmed/22242031 http://dx.doi.org/10.1155/2011/748194 |
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