3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol

In the title compound, C(15)H(21)NO(4)S, both hy­droxy groups on the piperidine ring are located in axial positions, whereas the tosyl group and the cyclo­propane ring are in equatorial positions. An intra­molecular O—H⋯O hydrogen bond occurs. In the crystal, mol­ecules form inversion dimers via pai...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Lin, Yong-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254563/
https://www.ncbi.nlm.nih.gov/pubmed/22259513
http://dx.doi.org/10.1107/S1600536811054420
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author Wang, Yi
Lin, Yong-Yue
author_facet Wang, Yi
Lin, Yong-Yue
author_sort Wang, Yi
collection PubMed
description In the title compound, C(15)H(21)NO(4)S, both hy­droxy groups on the piperidine ring are located in axial positions, whereas the tosyl group and the cyclo­propane ring are in equatorial positions. An intra­molecular O—H⋯O hydrogen bond occurs. In the crystal, mol­ecules form inversion dimers via pairs of O—H⋯O hydrogen bonds, generating cyclic R (4) (4)(8) motifs, as noted previously in related diols.
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spelling pubmed-32545632012-01-18 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol Wang, Yi Lin, Yong-Yue Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(21)NO(4)S, both hy­droxy groups on the piperidine ring are located in axial positions, whereas the tosyl group and the cyclo­propane ring are in equatorial positions. An intra­molecular O—H⋯O hydrogen bond occurs. In the crystal, mol­ecules form inversion dimers via pairs of O—H⋯O hydrogen bonds, generating cyclic R (4) (4)(8) motifs, as noted previously in related diols. International Union of Crystallography 2011-12-23 /pmc/articles/PMC3254563/ /pubmed/22259513 http://dx.doi.org/10.1107/S1600536811054420 Text en © Wang and Lin 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Yi
Lin, Yong-Yue
3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title_full 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title_fullStr 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title_full_unstemmed 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title_short 3-Cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
title_sort 3-cyclo­propyl-1-(4-methyl­phenyl­sulfon­yl)piperidine-3,5-diol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254563/
https://www.ncbi.nlm.nih.gov/pubmed/22259513
http://dx.doi.org/10.1107/S1600536811054420
work_keys_str_mv AT wangyi 3cyclopropyl14methylphenylsulfonylpiperidine35diol
AT linyongyue 3cyclopropyl14methylphenylsulfonylpiperidine35diol

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