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Genetic Interactions between Chromosomes 11 and 18 Contribute to Airway Hyperresponsiveness in Mice

We used two-dimensional quantitative trait locus analysis to identify interacting genetic loci that contribute to the native airway constrictor hyperresponsiveness to methacholine that characterizes A/J mice, relative to C57BL/6J mice. We quantified airway responsiveness to intravenous methacholine...

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Detalles Bibliográficos
Autores principales:	Ferreira, Caroline M., Chen, James L., Li, Jianrong, Shimomura, Kazuhiro, Yang, Xinan, Lussier, Yves A., Pinto, Lawrence H., Solway, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254621/ https://www.ncbi.nlm.nih.gov/pubmed/22253740 http://dx.doi.org/10.1371/journal.pone.0029579

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