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Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation

Apoptosis signal-regulating kinase 1 (ASK1), a member of the mitogen-activated protein kinase 3 family, is activated by oxidative stress. The death-signaling pathway mediated by ASK1 is inhibited by DJ-1, which is linked to recessively inherited Parkinson's disease (PD). Considering that DJ-1 d...

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Detalles Bibliográficos
Autores principales:	Lee, Kang-Woo, Zhao, Xin, Im, Joo-Young, Grosso, Hilary, Jang, Won Hee, Chan, Teresa W., Sonsalla, Patricia K., German, Dwight C., Ichijo, Hidenori, Junn, Eunsung, Mouradian, M. Maral
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254627/ https://www.ncbi.nlm.nih.gov/pubmed/22253830 http://dx.doi.org/10.1371/journal.pone.0029935

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