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Epigallocatechin-3-Gallate as a Potential Therapeutic Drug for TTR-Related Amyloidosis: “In Vivo” Evidence from FAP Mice Models

BACKGROUND: Familial amyloidotic polyneuropathy (FAP) is a neurodegenerative disease caused by the extracellular deposition of mutant transthyretin (TTR), with special involvement of the peripheral nervous system (PNS). Currently, hepatic transplantation is considered the most efficient therapy to h...

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Detalles Bibliográficos
Autores principales: Ferreira, Nelson, Saraiva, Maria João, Almeida, Maria Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254632/
https://www.ncbi.nlm.nih.gov/pubmed/22253829
http://dx.doi.org/10.1371/journal.pone.0029933