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Interleukin-1 Inhibition and Fatigue in Primary Sjögren's Syndrome – A Double Blind, Randomised Clinical Trial

OBJECTIVES: Fatigue is a major cause of disability in primary Sjögren's syndrome (pSS). Fatigue has similarities with sickness behaviour in animals; the latter mediated by pro-inflammatory cytokines, in particular interleukin (IL)-1, acting on neuronal brain cells. We hypothesised that IL-1 inh...

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Detalles Bibliográficos
Autores principales:	Norheim, Katrine Brække, Harboe, Erna, Gøransson, Lasse G., Omdal, Roald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254637/ https://www.ncbi.nlm.nih.gov/pubmed/22253903 http://dx.doi.org/10.1371/journal.pone.0030123

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