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DNA Display Selection of Peptide Ligands for a Full-Length Human G Protein-Coupled Receptor on CHO-K1 Cells

The G protein-coupled receptors (GPCRs), which form the largest group of transmembrane proteins involved in signal transduction, are major targets of currently available drugs. Thus, the search for cognate and surrogate peptide ligands for GPCRs is of both basic and therapeutic interest. Here we des...

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Detalles Bibliográficos
Autores principales: Doi, Nobuhide, Yamakawa, Natsuko, Matsumoto, Hideaki, Yamamoto, Yasutsugu, Nagano, Tetsuya, Matsumura, Nobutaka, Horisawa, Kenichi, Yanagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254644/
https://www.ncbi.nlm.nih.gov/pubmed/22253889
http://dx.doi.org/10.1371/journal.pone.0030084