Cargando…

DNA Display Selection of Peptide Ligands for a Full-Length Human G Protein-Coupled Receptor on CHO-K1 Cells

The G protein-coupled receptors (GPCRs), which form the largest group of transmembrane proteins involved in signal transduction, are major targets of currently available drugs. Thus, the search for cognate and surrogate peptide ligands for GPCRs is of both basic and therapeutic interest. Here we des...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doi, Nobuhide, Yamakawa, Natsuko, Matsumoto, Hideaki, Yamamoto, Yasutsugu, Nagano, Tetsuya, Matsumura, Nobutaka, Horisawa, Kenichi, Yanagawa, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254644/ https://www.ncbi.nlm.nih.gov/pubmed/22253889 http://dx.doi.org/10.1371/journal.pone.0030084

Ejemplares similares

Use of cDNA Tiling Arrays for Identifying Protein Interactions Selected by In Vitro Display Technologies
por: Horisawa, Kenichi, et al.
Publicado: (2008)

Affinity selection of DNA-binding protein complexes using mRNA display
por: Tateyama, Seiji, et al.
Publicado: (2006)

Structural Basis for Inhibition of the MDM2:p53 Interaction by an Optimized MDM2-Binding Peptide Selected with mRNA Display
por: Nagata, Takashi, et al.
Publicado: (2014)

mRNA Display Selection of an Optimized MDM2-Binding Peptide That Potently Inhibits MDM2-p53 Interaction
por: Shiheido, Hirokazu, et al.
Publicado: (2011)

MIP-2A Is a Novel Target of an Anilinoquinazoline Derivative for Inhibition of Tumour Cell Proliferation
por: Tokunaga, Mayuko, et al.
Publicado: (2013)

Bicistronic DNA display for in vitro selection of Fab fragments
por: Sumida, Takeshi, et al.
Publicado: (2009)

In Vitro Selection of Fab Fragments by mRNA Display and Gene-Linking Emulsion PCR
por: Sumida, Takeshi, et al.
Publicado: (2012)

In vitro evolution of single-chain antibodies using mRNA display
por: Fukuda, Isao, et al.
Publicado: (2006)

Rapid antibody selection by mRNA display on a microfluidic chip
por: Tabata, Noriko, et al.
Publicado: (2009)

Comparison of the Frequency of Functional SH3 Domains with Different Limited Sets of Amino Acids Using mRNA Display
por: Tanaka, Junko, et al.
Publicado: (2011)

High efficiency CHO cell display-based antibody maturation
por: Luo, Ruiqi, et al.
Publicado: (2020)

A Phthalimide Derivative That Inhibits Centrosomal Clustering Is Effective on Multiple Myeloma
por: Shiheido, Hirokazu, et al.
Publicado: (2012)

YEAST SURFACE DISPLAY OF FULL-LENGTH IGG FOR ENGINEERING MONOCLONAL AND BISPECIFIC ANTIBODIES
por: Jiang, Youwei
Publicado: (2023)

Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells
por: Stuible, Matthew, et al.
Publicado: (2021)

Simultaneous Maturation of Single Chain Antibody Stability and Affinity by CHO Cell Display
por: Luo, Ruiqi, et al.
Publicado: (2022)

Protein–protein interaction analysis by C-terminally specific fluorescence labeling and fluorescence cross-correlation spectroscopy
por: Oyama, Rieko, et al.
Publicado: (2006)

ChoK-Full of Potential: Choline Kinase in B Cell and T Cell Malignancies
por: Gokhale, Samantha, et al.
Publicado: (2021)

REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells
por: Rhiel, Laura, et al.
Publicado: (2014)

Antisense transcripts with rice full-length cDNAs
por: Osato, Naoki, et al.
Publicado: (2004)

Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor
por: Gutmann, Theresia, et al.
Publicado: (2018)

Full-length human GLP-1 receptor structure without orthosteric ligands
por: Wu, Fan, et al.
Publicado: (2020)

A Method to Produce and Purify Full-Length Recombinant Alpha Dystroglycan: Analysis of N- and O-Linked Monosaccharide Composition in CHO Cells with or without LARGE Overexpression
por: Yoon, Jung Hae, et al.
Publicado: (2013)

Selection of biophysically favorable antibody variants using a modified Flp-In CHO mammalian display platform
por: Huhtinen, Olli, et al.
Publicado: (2023)

Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells
por: Mavlyutov, Timur A, et al.
Publicado: (2007)

Radiobiological response of U251MG, CHO-K1 and V79 cell lines to accelerator-based boron neutron capture therapy
por: Sato, Eisuke, et al.
Publicado: (2018)

Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology
por: Galati, Clelia, et al.
Publicado: (2017)

Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy
por: Warhaut, Sven, et al.
Publicado: (2017)

Specific and quantitative labeling of biomolecules using click chemistry
por: Horisawa, Kenichi
Publicado: (2014)

Full-Color Realization of Micro-LED Displays
por: Wu, Yifan, et al.
Publicado: (2020)

Influence of cell culture media and feed supplements on cell metabolism and quality of IgG produced in CHO-K1, CHO-S, and CHO-DG44
por: Reinhart, David, et al.
Publicado: (2015)

Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows
por: NANIWA, Yousuke, et al.
Publicado: (2013)

REMD Simulations of Full-Length Alpha-Synuclein Together with Ligands Reveal Binding Region and Effect on Amyloid Conversion
por: Semenyuk, Pavel I.
Publicado: (2022)

Spontaneous Intramural Full-Length Dissection of Esophagus Treated with Surgical Intervention: Multidetector CT Diagnosis with Multiplanar Reformations and Virtual Endoscopic Display
por: Khil, Eun Kyung, et al.
Publicado: (2014)

Structure of Full-length Drosophila Cryptochrome
por: Zoltowski, Brian D., et al.
Publicado: (2011)

Retrovectors packaged in CHO cells to generate GLP-1-Fc stable expression CHO cell lines
por: Li, Jing, et al.
Publicado: (2019)

Modeling Signal Propagation Mechanisms and Ligand-Based Conformational Dynamics of the Hsp90 Molecular Chaperone Full-Length Dimer
por: Morra, Giulia, et al.
Publicado: (2009)

Single-particle analysis of full-length human poly(ADP-ribose) polymerase 1
por: Kouyama, Kenichi, et al.
Publicado: (2019)

Propagation Capacity of Phage Display Peptide Libraries Is Affected by the Length and Conformation of Displayed Peptide
por: Kamstrup Sell, Danna, et al.
Publicado: (2023)

Direct cell-fate conversion of somatic cells: Toward regenerative medicine and industries
por: HORISAWA, Kenichi, et al.
Publicado: (2020)

The role of pioneer transcription factors in the induction of direct cellular reprogramming()
por: Horisawa, Kenichi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s5t8f5u4qvi7boils5epn0s9r3