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Inhibition of Firefly Luciferase by General Anesthetics: Effect on In Vitro and In Vivo Bioluminescence Imaging

Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery. However, general anesthetics have been described as important inhibitors of the luciferase enzyme reaction. AIM: To investigate frequently...

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Detalles Bibliográficos
Autores principales:	Keyaerts, Marleen, Remory, Isabel, Caveliers, Vicky, Breckpot, Karine, Bos, Tomas J., Poelaert, Jan, Bossuyt, Axel, Lahoutte, Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254645/ https://www.ncbi.nlm.nih.gov/pubmed/22253879 http://dx.doi.org/10.1371/journal.pone.0030061

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