Laminar flow activation of ERK5 leads to cytoprotective effect via CHIP-mediated p53 ubiquitination in endothelial cells

Atherosclerosis is readily observed in areas where disturbed flow is formed, while the atheroprotective region is found in areas with steady laminar flow (L-flow). It has been established that L-flow protects endothelial cells against endothelial dysfunction, including apoptosis and inflammation. It...

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Detalles Bibliográficos
Autores principales: Lim, Jae Hyang, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254880/
https://www.ncbi.nlm.nih.gov/pubmed/22254155
http://dx.doi.org/10.5115/acb.2011.44.4.265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254880/
https://www.ncbi.nlm.nih.gov/pubmed/22254155
http://dx.doi.org/10.5115/acb.2011.44.4.265

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