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Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection

Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukoc...

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Autores principales: Heidari, Mohammad Hassan, Novin, Marefat Ghaffari, Ahmadi, Farzaneh, Khorshid, Mehran, Najafi, Tohid, Molouki, Aidin, Salehpour, Saghar, Bandehpour, Mojgan, Heidari, Matineh, Sato, Eimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254887/
https://www.ncbi.nlm.nih.gov/pubmed/22254162
http://dx.doi.org/10.5115/acb.2011.44.4.331
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author Heidari, Mohammad Hassan
Novin, Marefat Ghaffari
Ahmadi, Farzaneh
Khorshid, Mehran
Najafi, Tohid
Molouki, Aidin
Salehpour, Saghar
Bandehpour, Mojgan
Heidari, Matineh
Sato, Eimi
author_facet Heidari, Mohammad Hassan
Novin, Marefat Ghaffari
Ahmadi, Farzaneh
Khorshid, Mehran
Najafi, Tohid
Molouki, Aidin
Salehpour, Saghar
Bandehpour, Mojgan
Heidari, Matineh
Sato, Eimi
author_sort Heidari, Mohammad Hassan
collection PubMed
description Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy.
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spelling pubmed-32548872012-01-17 Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection Heidari, Mohammad Hassan Novin, Marefat Ghaffari Ahmadi, Farzaneh Khorshid, Mehran Najafi, Tohid Molouki, Aidin Salehpour, Saghar Bandehpour, Mojgan Heidari, Matineh Sato, Eimi Anat Cell Biol Original Article Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy. Korean Association of Anatomists 2011-12 2011-12-30 /pmc/articles/PMC3254887/ /pubmed/22254162 http://dx.doi.org/10.5115/acb.2011.44.4.331 Text en Copyright © 2011. Anatomy & Cell Biology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Heidari, Mohammad Hassan
Novin, Marefat Ghaffari
Ahmadi, Farzaneh
Khorshid, Mehran
Najafi, Tohid
Molouki, Aidin
Salehpour, Saghar
Bandehpour, Mojgan
Heidari, Matineh
Sato, Eimi
Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title_full Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title_fullStr Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title_full_unstemmed Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title_short Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection
title_sort increase in concentration of soluble hla-g in high-quality embryos after intracytoplasmic sperm injection
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254887/
https://www.ncbi.nlm.nih.gov/pubmed/22254162
http://dx.doi.org/10.5115/acb.2011.44.4.331
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