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Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia

Acute myeloid leukemia (AML) frequently comprises mutations in genes that cause perturbation in intracellular signaling pathways, thereby altering normal responses to growth factors and cytokines. Such oncogenic cellular signal transduction may be therapeutic if targeted directly or through epigenet...

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Detalles Bibliográficos
Autores principales:	Skavland, J, Jørgensen, K M, Hadziavdic, K, Hovland, R, Jonassen, I, Bruserud, Ø, Gjertsen, B T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255270/ https://www.ncbi.nlm.nih.gov/pubmed/22829110 http://dx.doi.org/10.1038/bcj.2011.2

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