DESIGN AND EVALUATION OF A METRONIDAZOLE CENTRAL CORE MATRIX TABLET

In this paper, a study of different concentration of HPMC K 15 M exerts influence on the drug release process from a new controlled drug delivery system has been realized in order to obtain a constant release rate during a prolonged period of time, for a programmed drug release. The drug release pro...

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Detalles Bibliográficos
Autores principales: Nagaich, Upendra, Chaudhary, Vandana, Tonpay, S.D., Karki, Roopa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255394/
https://www.ncbi.nlm.nih.gov/pubmed/22247836
Descripción
Sumario:In this paper, a study of different concentration of HPMC K 15 M exerts influence on the drug release process from a new controlled drug delivery system has been realized in order to obtain a constant release rate during a prolonged period of time, for a programmed drug release. The drug release profiles obtained for the different batches have shown an interesting relationship between the particle size of the channeling agent used and the length of different operational periods.

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