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Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals

Swarna makshika (chalcopyrite) bhasma (SMB) has been used for different therapeutic purposes since long in Ayurveda. The present study is conducted to evaluate the effect of conventionally prepared SMB on different bio-chemical parameters in experimental animals, for providing scientific data base f...

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Autores principales: Mohapatra, Sudhaldev, Jha, C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255449/
https://www.ncbi.nlm.nih.gov/pubmed/22253508
http://dx.doi.org/10.4103/0975-9476.90773
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author Mohapatra, Sudhaldev
Jha, C.B.
author_facet Mohapatra, Sudhaldev
Jha, C.B.
author_sort Mohapatra, Sudhaldev
collection PubMed
description Swarna makshika (chalcopyrite) bhasma (SMB) has been used for different therapeutic purposes since long in Ayurveda. The present study is conducted to evaluate the effect of conventionally prepared SMB on different bio-chemical parameters in experimental animals, for providing scientific data base for its logical use in clinical practice. The genuine SMB was prepared by following classical techniques of shodhana and marana most commonly used by different Ayurvedic drug manufacturers. Shodhana was done by roasting raw swarna makshika with lemon juice for three days and marana was performed by 11 putas. The experimental animals (rats) were divided into two groups. SMB mixed with diluted honey was administered orally in therapeutic dose to Group SMB and diluted honey only was administered to vehicle control Group, for 30 days. The blood samples were collected twice, after 15 days and after 30 days of drug administration and different biochemical investigations were done. Biochemical parameters were chosen based on references from Ayurvedic classics and contemporary medicine. It was observed that Hb% was found significantly increased and LDL and VLDL were found significantly decreased in Group SMB when compared with vehicle control group. This experimental data will help the clinician for the logical use of SMB in different disease conditions with findings like low Hb% and high LDL, VLDL levels.
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spelling pubmed-32554492012-01-17 Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals Mohapatra, Sudhaldev Jha, C.B. J Ayurveda Integr Med Original Research Article Swarna makshika (chalcopyrite) bhasma (SMB) has been used for different therapeutic purposes since long in Ayurveda. The present study is conducted to evaluate the effect of conventionally prepared SMB on different bio-chemical parameters in experimental animals, for providing scientific data base for its logical use in clinical practice. The genuine SMB was prepared by following classical techniques of shodhana and marana most commonly used by different Ayurvedic drug manufacturers. Shodhana was done by roasting raw swarna makshika with lemon juice for three days and marana was performed by 11 putas. The experimental animals (rats) were divided into two groups. SMB mixed with diluted honey was administered orally in therapeutic dose to Group SMB and diluted honey only was administered to vehicle control Group, for 30 days. The blood samples were collected twice, after 15 days and after 30 days of drug administration and different biochemical investigations were done. Biochemical parameters were chosen based on references from Ayurvedic classics and contemporary medicine. It was observed that Hb% was found significantly increased and LDL and VLDL were found significantly decreased in Group SMB when compared with vehicle control group. This experimental data will help the clinician for the logical use of SMB in different disease conditions with findings like low Hb% and high LDL, VLDL levels. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3255449/ /pubmed/22253508 http://dx.doi.org/10.4103/0975-9476.90773 Text en Copyright: © Journal of Ayurveda and Integrative Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Mohapatra, Sudhaldev
Jha, C.B.
Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title_full Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title_fullStr Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title_full_unstemmed Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title_short Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
title_sort evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255449/
https://www.ncbi.nlm.nih.gov/pubmed/22253508
http://dx.doi.org/10.4103/0975-9476.90773
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