Cargando…

Imatinib causes epigenetic alterations of PTEN gene via upregulation of DNA methyltransferases and polycomb group proteins

We have recently reported the possible imatinib-resistant mechanism; long-term exposure of leukemia cells to imatinib downregulated levels of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) via hypermethylation of its promoter region (Leukemia 2010; 24: 1631). The present study explor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishioka, C, Ikezoe, T, Yang, J, Udaka, K, Yokoyama, A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255508/ https://www.ncbi.nlm.nih.gov/pubmed/22829096 http://dx.doi.org/10.1038/bcj.2011.33

Ejemplares similares

DNA Methyltransferase 3 (MET3) is regulated by Polycomb group complex during Arabidopsis endosperm development
por: Tirot, Louis, et al.
Publicado: (2022)

Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme
por: Li, Gang, et al.
Publicado: (2013)

Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines
por: Feng, Helin, et al.
Publicado: (2018)

Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins
por: Khan, Sheraz, et al.
Publicado: (2018)

A repetitive elements perspective in Polycomb epigenetics
por: Casa, Valentina, et al.
Publicado: (2012)

Digital paradigm for Polycomb epigenetic switching and memory
por: Menon, Govind, et al.
Publicado: (2021)

Phenotypic pliancy and the breakdown of epigenetic polycomb mechanisms
por: Lambros, Maryl, et al.
Publicado: (2023)

SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing
por: Wakeling, Luisa A, et al.
Publicado: (2015)

Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer
por: Cai, Ying, et al.
Publicado: (2018)

Role of Polycomb Group Proteins in the DNA Damage Response – A Reassessment
por: Chandler, Hollie, et al.
Publicado: (2014)

Alternative Epigenetic Chromatin States of Polycomb Target Genes
por: Schwartz, Yuri B., et al.
Publicado: (2010)

Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells
por: Nishioka, Chie, et al.
Publicado: (2015)

Targeting of polycombs to DNA in EMT
por: Battistelli, Cecilia, et al.
Publicado: (2017)

Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo
por: Nishioka, Chie, et al.
Publicado: (2015)

The functions of polycomb group proteins in T cells
por: Li, Ting
Publicado: (2022)

Single-molecule imaging of epigenetic complexes in living cells: insights from studies on Polycomb group proteins
por: Brown, Kyle, et al.
Publicado: (2021)

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression
por: Long, Shengwen, et al.
Publicado: (2023)

The Arginine Methyltransferase PRMT6 Cooperates with Polycomb Proteins in Regulating HOXA Gene Expression
por: Stein, Claudia, et al.
Publicado: (2016)

The polycomb group protein EZH2 induces epithelial–mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter
por: Gan, Lu, et al.
Publicado: (2018)

The Role of Polycomb Group Protein BMI1 in DNA Repair and Genomic Stability
por: Fitieh, Amira, et al.
Publicado: (2021)

DNA binding by polycomb-group proteins: searching for the link to CpG islands
por: Owen, Brady M, et al.
Publicado: (2022)

Segregating Variation in the Polycomb Group Gene cramped Alters the Effect of Temperature on Multiple Traits
por: Gibert, Jean-Michel, et al.
Publicado: (2011)

Helicobacter pylori DNA methyltransferases and the epigenetic field effect in cancerization
por: Sitaraman, Ramakrishnan
Publicado: (2014)

Using computational modelling to reveal mechanisms of epigenetic Polycomb control
por: Lövkvist, Cecilia, et al.
Publicado: (2021)

Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing
por: del Olmo, Iván, et al.
Publicado: (2016)

The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis
por: Spaapen, Frank, et al.
Publicado: (2013)

O-GlcNAcylation, an Epigenetic Mark. Focus on the Histone Code, TET Family Proteins, and Polycomb Group Proteins
por: Dehennaut, Vanessa, et al.
Publicado: (2014)

The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets
por: Van Dessel, Nele, et al.
Publicado: (2010)

Evolution of Polycomb-group function in the green lineage
por: Schubert, Daniel
Publicado: (2019)

Mechanisms of Polycomb group protein function in cancer
por: Parreno, Victoria, et al.
Publicado: (2022)

Human Intelligence and Polymorphisms in the DNA Methyltransferase Genes Involved in Epigenetic Marking
por: Haggarty, Paul, et al.
Publicado: (2010)

Short germ insects utilize both the ancestral and derived mode of Polycomb group-mediated epigenetic silencing of Hox genes
por: Matsuoka, Yuji, et al.
Publicado: (2015)

Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication
por: Peña-Diaz, Javier, et al.
Publicado: (2013)

Roles of the Polycomb group proteins in stem cells and cancer
por: Richly, H, et al.
Publicado: (2011)

The Central Role of EED in the Orchestration of Polycomb Group Complexes
por: Cao, Qi, et al.
Publicado: (2014)

Polycomb group expression signatures in the malignant progression of gliomas
por: Hu, Qi, et al.
Publicado: (2017)

The relevance of polycomb group proteins to the development of psychiatric disorders
por: Peedicayil, Jacob
Publicado: (2022)

Polycomb group genes are required for neuronal pruning in Drosophila
por: Bu, Shufeng, et al.
Publicado: (2023)

Impairment of Lamin A/C-Polycomb crosstalk as a possible epigenetic cause of Emery Dreifuss Muscular Dystrophy (EDMD)
por: Lanzuolo, Chiara
Publicado: (2015)

Epigenetic Remodeling of Meiotic Crossover Frequency in Arabidopsis thaliana DNA Methyltransferase Mutants
por: Yelina, Nataliya E., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_f0f8pl2ler1rlj28ogjr2bedao