The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma

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Aberrant activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway has been reported to promote proliferation and survival of Hodgkin and Reed–Sternberg cells of Hodgkin lymphoma (HL). We investigated the activity of the JAK inhibitor AZD1480 in HL-derived...

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Detalles Bibliográficos
Autores principales: Derenzini, E, Lemoine, M, Buglio, D, Katayama, H, Ji, Y, Davis, R E, Sen, S, Younes, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255510/
https://www.ncbi.nlm.nih.gov/pubmed/22829094
http://dx.doi.org/10.1038/bcj.2011.46
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