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A zebrafish transgenic model of Ewing’s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

Ewing’s sarcoma, a malignant bone tumor of children and young adults, is a member of the small-round-blue-cell tumor family. Ewing’s sarcoma family tumors (ESFTs), which include peripheral primitive neuroectodermal tumors (PNETs), are characterized by chromosomal translocations that generate fusions...

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Detalles Bibliográficos
Autores principales: Leacock, Stefanie W., Basse, Audrey N., Chandler, Garvin L., Kirk, Anne M., Rakheja, Dinesh, Amatruda, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255547/
https://www.ncbi.nlm.nih.gov/pubmed/21979944
http://dx.doi.org/10.1242/dmm.007401