Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

PTEN (phosphatase and tensin homologue deleted on chromosome TEN) is the major negative regulator of phosphatidylinositol 3-kinase signaling and has cell-specific functions including tumor suppression. Nuclear localization of PTEN is vital for tumor suppression; however, outside of cancer, the molec...

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Detalles Bibliográficos
Autores principales: Howitt, Jason, Lackovic, Jenny, Low, Ley-Hian, Naguib, Adam, Macintyre, Alison, Goh, Choo-Peng, Callaway, Jennifer K., Hammond, Vicki, Thomas, Tim, Dixon, Matthew, Putz, Ulrich, Silke, John, Bartlett, Perry, Yang, Baoli, Kumar, Sharad, Trotman, Lloyd C., Tan, Seong-Seng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255971/
https://www.ncbi.nlm.nih.gov/pubmed/22213801
http://dx.doi.org/10.1083/jcb.201105009

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