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A novel function for Cyclin A2: Control of cell invasion via RhoA signaling

Cyclin A2 plays a key role in cell cycle regulation. It is essential in embryonic cells and in the hematopoietic lineage yet dispensable in fibroblasts. In this paper, we demonstrate that Cyclin A2–depleted cells display a cortical distribution of actin filaments and increased migration. These defec...

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Detalles Bibliográficos
Autores principales: Arsic, Nikola, Bendris, Nawal, Peter, Marion, Begon-Pescia, Christina, Rebouissou, Cosette, Gadéa, Gilles, Bouquier, Nathalie, Bibeau, Frédéric, Lemmers, Bénédicte, Blanchard, Jean Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255987/
https://www.ncbi.nlm.nih.gov/pubmed/22232705
http://dx.doi.org/10.1083/jcb.201102085