Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R

The Leiden Longevity Study consists of families that express extended survival across generations, decreased morbidity in middle-age, and beneficial metabolic profiles. To identify which pathways drive this complex phenotype of familial longevity and healthy aging, we performed a genome-wide gene ex...

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Detalles Bibliográficos
Autores principales: Passtoors, Willemijn M., Boer, Judith M., Goeman, Jelle J., van den Akker, Erik B., Deelen, Joris, Zwaan, Bas J., Scarborough, Ann, van der Breggen, Ruud, Vossen, Rolf H. A. M., Houwing-Duistermaat, Jeanine J., van Ommen, Gert Jan B., Westendorp, Rudi G. J., van Heemst, Diana, de Craen, Anton J. M., White, Andrew J., Gunn, David A., Beekman, Marian, Slagboom, P. Eline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256132/
https://www.ncbi.nlm.nih.gov/pubmed/22247756
http://dx.doi.org/10.1371/journal.pone.0027759

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