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Characterization of the Endothelial Cell Cytoskeleton following HLA Class I Ligation

BACKGROUND: Vascular endothelial cells (ECs) are a target of antibody-mediated allograft rejection. In vitro, when the HLA class I molecules on the surface of ECs are ligated by anti-HLA class I antibodies, cell proliferation and survival pathways are activated and this is thought to contribute to t...

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Detalles Bibliográficos
Autores principales: Ziegler, Mary E., Souda, Puneet, Jin, Yi-Ping, Whitelegge, Julian P., Reed, Elaine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256144/
https://www.ncbi.nlm.nih.gov/pubmed/22247778
http://dx.doi.org/10.1371/journal.pone.0029472