Genetically-Engineered Pig-to-Baboon Liver Xenotransplantation: Histopathology of Xenografts and Native Organs

Orthotopic liver transplantation was carried out in baboons using wild-type (WT, n = 1) or genetically-engineered pigs (α1,3-galactosyltransferase gene-knockout, GTKO), n = 1; GTKO pigs transgenic for human CD46, n = 7) and a clinically-acceptable immunosuppressive regimen. Biopsies were obtained fr...

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Detalles Bibliográficos
Autores principales: Ekser, Burcin, Klein, Edwin, He, Jing, Stolz, Donna B., Echeverri, Gabriel J., Long, Cassandra, Lin, Chih Che, Ezzelarab, Mohamed, Hara, Hidetaka, Veroux, Massimiliano, Ayares, David, Cooper, David K. C., Gridelli, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256162/
https://www.ncbi.nlm.nih.gov/pubmed/22247784
http://dx.doi.org/10.1371/journal.pone.0029720

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