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Inter-Relationship between Testicular Dysgenesis and Leydig Cell Function in the Masculinization Programming Window in the Rat

The testicular dysgenesis syndrome (TDS) hypothesis proposes that maldevelopment of the testis, irrespective of cause, leads to malfunction of the somatic (Leydig, Sertoli) cells and consequent downstream TDS disorders. Studies in rats exposed in utero to di(n-butyl) phthalate (DBP) have strongly su...

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Detalles Bibliográficos
Autores principales: van den Driesche, Sander, Kolovos, Petros, Platts, Sophie, Drake, Amanda J., Sharpe, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256232/
https://www.ncbi.nlm.nih.gov/pubmed/22253897
http://dx.doi.org/10.1371/journal.pone.0030111

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