Analysis of genomic aberrations and gene expression profiling identifies novel lesions and pathways in myeloproliferative neoplasms

Polycythemia vera (PV), essential thrombocythemia and primary myelofibrosis, are myeloproliferative neoplasms (MPNs) with distinct clinical features and are associated with the JAK2V617F mutation. To identify genomic anomalies involved in the pathogenesis of these disorders, we profiled 87 MPN patie...

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Detalles Bibliográficos
Autores principales: Rice, K L, Lin, X, Wolniak, K, Ebert, B L, Berkofsky-Fessler, W, Buzzai, M, Sun, Y, Xi, C, Elkin, P, Levine, R, Golub, T, Gilliland, D G, Crispino, J D, Licht, J D, Zhang, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256752/
https://www.ncbi.nlm.nih.gov/pubmed/22829077
http://dx.doi.org/10.1038/bcj.2011.39

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