AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model

Multiple myeloma (MM) is a malignant neoplasm of plasma cells. Although new molecular targeting agents against MM have been developed based on the better understanding of the underlying pathogenesis, MM still remains an incurable disease. We previously demonstrated that β-catenin, a downstream effec...

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Detalles Bibliográficos
Autores principales: Yao, H, Ashihara, E, Strovel, J W, Nakagawa, Y, Kuroda, J, Nagao, R, Tanaka, R, Yokota, A, Takeuchi, M, Hayashi, Y, Shimazaki, C, Taniwaki, M, Strand, K, Padia, J, Hirai, H, Kimura, S, Maekawa, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256754/
https://www.ncbi.nlm.nih.gov/pubmed/22829079
http://dx.doi.org/10.1038/bcj.2011.41

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