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Immunization of Mice With Vibrio cholerae Outer-Membrane Vesicles Protects Against Hyperinfectious Challenge and Blocks Transmission

Background. Vibrio cholerae excreted by cholera patients is “hyperinfectious” (HI), which can be modeled by passage through infant mice. Immunization of adult female mice with V. cholerae outer-membrane vesicles (OMVs) passively protects suckling mice from challenge. Although V. cholerae is unable t...

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Detalles Bibliográficos
Autores principales: Bishop, Anne L., Tarique, Abdullah A., Patimalla, Bharathi, Calderwood, Stephen B., Qadri, Firdausi, Camilli, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256948/
https://www.ncbi.nlm.nih.gov/pubmed/22147790
http://dx.doi.org/10.1093/infdis/jir756

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