Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE

The integrin α4β1 (VLA-4) is used by encephalitogenic T cells to enter the central nervous system (CNS). However, both Th1 and Th17 cells are capable of inducing experimental autoimmune encephalomyelitis (EAE), and the molecular cues mediating the infiltration of Th1 versus Th17 cells into the CNS h...

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Detalles Bibliográficos
Autores principales: Rothhammer, Veit, Heink, Sylvia, Petermann, Franziska, Srivastava, Rajneesh, Claussen, Malte C., Hemmer, Bernhard, Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256959/
https://www.ncbi.nlm.nih.gov/pubmed/22025301
http://dx.doi.org/10.1084/jem.20110434

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