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IGSF4 is a novel TCR ζ-chain–interacting protein that enhances TCR-mediated signaling

Immunoglobulin superfamily member 4 (IGSF4) is a known ligand of CRTAM, a receptor expressed in activated NKT and CD8(+) T cells, but its function in T cell immunity has not been elucidated. In this study, we show that IGSF4 directly interacts with the T cell receptor (TCR) ζ-chain and enhances TCR...

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Detalles Bibliográficos
Autores principales:	Kim, Hye-Ran, Jeon, Byeong-Hun, Lee, Hyun-Su, Im, Sin-Hyeog, Araki, Masatake, Araki, Kimi, Yamamura, Ken-ichi, Choi, Suck-Chei, Park, Do-Sim, Jun, Chang-Duk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256964/ https://www.ncbi.nlm.nih.gov/pubmed/22084409 http://dx.doi.org/10.1084/jem.20110853

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