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Two modes of lytic granule fusion during degranulation by natural killer cells

Lytic granules in cytotoxic lymphocytes, which include T cells and natural killer (NK) cells, are secretory lysosomes that release their content upon fusion with the plasma membrane (PM), a process known as degranulation. Although vesicle exocytosis has been extensively studied in endocrine and neur...

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Detalles Bibliográficos
Autores principales: Liu, Dongfang, Martina, Jose A, Wu, Xufeng S, Hammer III, John A, Long, Eric O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257049/
https://www.ncbi.nlm.nih.gov/pubmed/21483445
http://dx.doi.org/10.1038/icb.2010.167