Structural Requirements of N-Substituted Spiropiperidine Analogues as Agonists of Nociceptin/Orphanin FQ Receptor

The nociceptin/orphanin FQ (NOP) receptor is involved in a wide range of biological functions, including pain, anxiety, depression and drug abuse. Especially, its agonists have great potential to be developed into anxiolytics. In this work, both the ligand- and receptor-based three-dimensional quant...

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Detalles Bibliográficos
Autores principales: Bao, Pingping, Zhang, Xiaole, Ren, Hong, Li, Yan, Mu, Zulin, Zhang, Shuwei, Li, Guohui, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257111/
https://www.ncbi.nlm.nih.gov/pubmed/22272114
http://dx.doi.org/10.3390/ijms12128961

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