Differential Motor Neuron Impairment and Axonal Regeneration in Sporadic and Familiar Amyotrophic Lateral Sclerosis with SOD-1 Mutations: Lessons from Neurophysiology

Amyotrophic Lateral Sclerosis (ALS) is a degenerative disorder of the motor system. About 10% of cases are familial and 20% of these families have point mutations in the Cu/Zn superoxide dismutase 1 (SOD-1) gene. SOD-1 catalyses the superoxide radical (O(−2)) into hydrogen peroxide and molecular oxy...

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Detalles Bibliográficos
Autores principales: Bocci, Tommaso, Pecori, Chiara, Giorli, Elisa, Briscese, Lucia, Tognazzi, Silvia, Caleo, Matteo, Sartucci, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257125/
https://www.ncbi.nlm.nih.gov/pubmed/22272128
http://dx.doi.org/10.3390/ijms12129203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257125/
https://www.ncbi.nlm.nih.gov/pubmed/22272128
http://dx.doi.org/10.3390/ijms12129203

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