NMR Studies on Structure and Dynamics of the Monomeric Derivative of BS-RNase: New Insights for 3D Domain Swapping

Three-dimensional domain swapping is a common phenomenon in pancreatic-like ribonucleases. In the aggregated state, these proteins acquire new biological functions, including selective cytotoxicity against tumour cells. RNase A is able to dislocate both N- and C-termini, but usually this process req...

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Detalles Bibliográficos
Autores principales: Spadaccini, Roberta, Ercole, Carmine, Gentile, Maria A., Sanfelice, Domenico, Boelens, Rolf, Wechselberger, Rainer, Batta, Gyula, Bernini, Andrea, Niccolai, Neri, Picone, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257227/
https://www.ncbi.nlm.nih.gov/pubmed/22253705
http://dx.doi.org/10.1371/journal.pone.0029076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257227/
https://www.ncbi.nlm.nih.gov/pubmed/22253705
http://dx.doi.org/10.1371/journal.pone.0029076

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