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A Whole Cell Assay to Measure Caspase-6 Activity by Detecting Cleavage of Lamin A/C

Caspase-6 is a cysteinyl protease implicated in neurodegenerative conditions including Alzheimer's and Huntington's disease making it an attractive target for therapeutic intervention. A greater understanding of the role of caspase-6 in disease has been hampered by a lack of suitable cellu...

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Detalles Bibliográficos
Autores principales:	Mintzer, Robert, Ramaswamy, Sreemathy, Shah, Kinjalkumar, Hannoush, Rami N., Pozniak, Christine D., Cohen, Frederick, Zhao, Xianrui, Plise, Emile, Lewcock, Joseph W., Heise, Christopher E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257251/ https://www.ncbi.nlm.nih.gov/pubmed/22253931 http://dx.doi.org/10.1371/journal.pone.0030376

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